Manager/Sr. Manager - Production (Liquid Oral)

Job Description:

Position:      Manager/Sr. Manager - Production (Liquid Oral)

Location:       Ahmedabad

Experience:    8 - 12 Years

Industries:     Pharma  

Responsibilities

• Oral Liquid Manufacturing
• Plan and execute manufacturing of syrups, suspensions, solutions, emulsions and other oral liquid formulations.
• Ensure manufacturing activities are carried out as per approved BMR/BPR, SOPs and validated processes.
• Monitor dispensing, charging, mixing, homogenization, heating/cooling, filtration and bulk transfer operations.
• Ensure proper control of critical process parameters such as mixing time, temperature, pH, viscosity, specific gravity and bulk yield, as applicable.
• Ensure appropriate hold-time controls for bulk products and intermediates.
• Review manufacturing process deviations, process failures and yield variations and initiate CAPA where required.
• Ensure line clearance, equipment status and area readiness before starting each batch.
• Coordinate with QA, QC, Engineering, Warehouse and Planning for smooth batch execution.
• Filling Operations
• Manage liquid filling operations for bottles/containers using automatic/semi- automatic filling machines.
• Ensure correct filling volume, filling accuracy, container/closure compatibility and machine performance.
• Monitor filling line parameters and minimize rejection, leakage, spillage and product loss.
• Ensure proper cleaning, changeover and line clearance of filling equipment.
• Ensure filling equipment qualification, preventive maintenance and calibration requirements are followed.
• Investigate filling-related defects and implement corrective/preventive actions.
• Packing Operations
• Manage primary and secondary packing operations including bottle washing, filling, capping, induction sealing, labelling, cartoning and shipper packing, as applicable.
• Ensure correct packing material, artwork, batch details, coding and reconciliation.
• Ensure proper line clearance and prevention of mix-ups and cross- contamination.
• Monitor packing line efficiency, productivity and rejection.
• Ensure reconciliation of printed and packaging materials.
• Coordinate with QA for online checks and final packing clearance.
• Production Planning & Productivity
• Prepare daily/weekly/monthly production plans in coordination with PPC.
• Ensure achievement of production targets within planned timelines.
• Optimize manpower, machine utilization, batch cycle time and material consumption.
• Monitor OEE, yield, downtime, rejection and line efficiency.
• Identify bottlenecks and implement productivity improvement initiatives.
• Control manufacturing losses and improve overall cost effectiveness.
• GMP & Regulatory Compliance:
• Ensure strict compliance with cGMP, GDP, data integrity and applicable regulatory requirements.
• Maintain complete and accurate batch manufacturing and packing documentation.
• Ensure adherence to SOPs, BMR/BPR, change controls, deviations, CAPA and investigation requirements.
• Support internal, customer and regulatory inspections/audits.
• Ensure proper implementation of qualification, validation and cleaning- validation requirements.
• Maintain high standards of housekeeping, personnel hygiene and safety.
• People Management:
• Lead and develop Production Officers, Executives, Supervisors and operators.
• Plan manpower deployment across manufacturing, filling and packing activities.
• Conduct training on GMP, SOPs, safety, equipment operation and process requirements.
• Identify training needs and improve technical competency of the team.
• Promote a culture of quality, discipline, ownership and continuous improvement.
• Cross-Functional Coordination:
• Coordinate with QA/QC for sampling, release, deviations and investigations.
• Coordinate with Engineering for equipment breakdowns, preventive maintenance and utilities.
• Coordinate with Warehouse for timely availability of raw materials and packing materials.
• Coordinate with PPC for production planning and dispatch requirements.
• Coordinate with Validation/Projects for new equipment, process validation and technology transfer activities.